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Bioreactor Gas-Permeable Tube

Precision Gas Transfer Solution for Cell Culture & Bioprocessing

Our gas-permeable tubes are specially engineered for integration into bioreactors, fermenters, and cell culture systems, where controlled and efficient gas exchange is critical for optimal biological performance. Made with high-purity sintered stainless steel or microporous PTFE, these tubes ensure uniform oxygen/CO₂ diffusion, chemical resistance, and biocompatibility, enabling stable and sterile gas transfer in the most demanding GMP-grade bioprocessing environments.


Why Choose Our Gas-Permeable Tubes for Bioreactors?

✅ Controlled Gas Diffusion
Enables consistent transfer of O₂, CO₂, N₂, or custom gas mixtures into culture media or headspace with predictable diffusion rates.

✅ Sterilizable & Reusable
Built for steam-in-place (SIP) and autoclave sterilization, ensuring long-term use in regulated bioprocessing systems.

✅ Low Extractables & Leachables
Made from materials that comply with USP Class VI, FDA CFR 21, and ISO 10993 for cell-safe operation.

✅ Robust & Non-Collapsible
Resistant to vacuum and mechanical pressure. Does not kink, collapse, or degrade in long-term use—even under agitation or pressure shifts.

✅ Versatile Gas Management
Supports oxygenation, CO₂ stripping, nitrogen purging, or headspace control for both aerobic and anaerobic processes.


Applications in Biotech & Life Sciences

Mammalian & Insect Cell Culture
Enables precise oxygen transfer rates (OTR) for CHO, HEK, and Sf9 cell lines.


Microbial Fermentation (E. coli, yeast, etc.)
Used in lab-scale and pilot-scale bioreactors to maintain proper aerobic/anaerobic balance.


Tissue Engineering & Regenerative Medicine
Supports gas-permeable scaffolding environments for 3D tissue culture and organoid growth.


Vaccine & mAb Production
Assists in controlled gas exchange during upstream processing in single-use or stainless steel bioreactors.

Gene Therapy & Viral Vector Production
Ensures stable gas environment during lentivirus, AAV, or retrovirus production in BSL-2/BSL-3 setups.


Bioreactor Gas-Permeable Tube

Technical Specifications

ParameterDescription
Material OptionsSintered 316L SS / Microporous PTFE / Titanium
Typical Pore Size0.2 – 10 μm
Outer Diameter6 – 25 mm (customizable)
Length100 – 2000 mm
Max Temperature200 – 600°C (depending on material)
Max Operating PressureUp to 3 MPa
Gas CompatibilityO₂, CO₂, N₂, Air, Ar, He
Surface TreatmentElectropolished, Passivated, Hydrophilic or Hydrophobic
SterilizationSIP, Autoclave, Gamma, EtO
ComplianceUSP Class VI, FDA, ISO 10993, RoHS


Integration Options

Custom Connection Ends


Bioreactor Integration


Optional Add-ons


Key Advantages for Bioprocess Engineers

✔ Improves Cell Viability & Yield
Maintains optimal gas exchange rate to minimize hypoxia and improve cell density and productivity.

✔ Reduced Shear & Bubble Damage
Gas diffuses gradually without causing large gas bubbles that can damage delicate cells or proteins.

✔ Compact & Scalable
Works for lab-scale (1–5 L), pilot-scale (20–200 L), and production-scale (>1000 L) bioreactors.

✔ Long Service Life
High durability under repeated sterilization and operation cycles reduces downtime and consumable costs.


Custom Fabrication & OEM Options

We offer tailored solutions to match your specific bioreactor geometry, gas transfer rates, and regulatory requirements.

Available Customizations:


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