Our gas-permeable tubes are specially engineered for integration into bioreactors, fermenters, and cell culture systems, where controlled and efficient gas exchange is critical for optimal biological performance. Made with high-purity sintered stainless steel or microporous PTFE, these tubes ensure uniform oxygen/CO₂ diffusion, chemical resistance, and biocompatibility, enabling stable and sterile gas transfer in the most demanding GMP-grade bioprocessing environments.
✅ Controlled Gas Diffusion
Enables consistent transfer of O₂, CO₂, N₂, or custom gas mixtures into culture media or headspace with predictable diffusion rates.
✅ Sterilizable & Reusable
Built for steam-in-place (SIP) and autoclave sterilization, ensuring long-term use in regulated bioprocessing systems.
✅ Low Extractables & Leachables
Made from materials that comply with USP Class VI, FDA CFR 21, and ISO 10993 for cell-safe operation.
✅ Robust & Non-Collapsible
Resistant to vacuum and mechanical pressure. Does not kink, collapse, or degrade in long-term use—even under agitation or pressure shifts.
✅ Versatile Gas Management
Supports oxygenation, CO₂ stripping, nitrogen purging, or headspace control for both aerobic and anaerobic processes.
Mammalian & Insect Cell Culture
Enables precise oxygen transfer rates (OTR) for CHO, HEK, and Sf9 cell lines.
Microbial Fermentation (E. coli, yeast, etc.)
Used in lab-scale and pilot-scale bioreactors to maintain proper aerobic/anaerobic balance.
Tissue Engineering & Regenerative Medicine
Supports gas-permeable scaffolding environments for 3D tissue culture and organoid growth.
Vaccine & mAb Production
Assists in controlled gas exchange during upstream processing in single-use or stainless steel bioreactors.
Gene Therapy & Viral Vector Production
Ensures stable gas environment during lentivirus, AAV, or retrovirus production in BSL-2/BSL-3 setups.
Parameter | Description |
---|---|
Material Options | Sintered 316L SS / Microporous PTFE / Titanium |
Typical Pore Size | 0.2 – 10 μm |
Outer Diameter | 6 – 25 mm (customizable) |
Length | 100 – 2000 mm |
Max Temperature | 200 – 600°C (depending on material) |
Max Operating Pressure | Up to 3 MPa |
Gas Compatibility | O₂, CO₂, N₂, Air, Ar, He |
Surface Treatment | Electropolished, Passivated, Hydrophilic or Hydrophobic |
Sterilization | SIP, Autoclave, Gamma, EtO |
Compliance | USP Class VI, FDA, ISO 10993, RoHS |
Custom Connection Ends
Tri-Clamp
Hose barb
NPT / BSP threaded
Welded flange
Sanitary fittings
Bioreactor Integration
Compatible with glass, stainless steel, and single-use bioreactor systems
Inline or sparging integration in top-entry, bottom-entry, or internal loop configurations
Optional Add-ons
Flow control valves
Pressure regulators
Oxygen concentration sensors
Gas mixers
✔ Improves Cell Viability & Yield
Maintains optimal gas exchange rate to minimize hypoxia and improve cell density and productivity.
✔ Reduced Shear & Bubble Damage
Gas diffuses gradually without causing large gas bubbles that can damage delicate cells or proteins.
✔ Compact & Scalable
Works for lab-scale (1–5 L), pilot-scale (20–200 L), and production-scale (>1000 L) bioreactors.
✔ Long Service Life
High durability under repeated sterilization and operation cycles reduces downtime and consumable costs.
We offer tailored solutions to match your specific bioreactor geometry, gas transfer rates, and regulatory requirements.
Available Customizations:
Tube diameter & length
Gas permeability & pore size
Integration fittings
Sterile packaging
Laser marking or serial tracking
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